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Comparison of the Effects of Oral Arnebia Euchroma and Oral ANGIPARS on Wounds in Diabetic Rats
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| Author:
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ALI ISHARIF, ELHAM SHAFIEI, MORTEZA HOSSEINZADEH
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| Abstract:
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Diabetic foot ulcer is one of the most common causes of amputation and imposes high social costs. The present study
was conducted to evaluate the effect of oral arnebia euchroma extract on wounds in diabetic rats and was compared
with oral and topical forms of ANGIPARS.Thirty diabetic male Wistar rats were categorized into different groups
with similar wounds, and were treated with oral and topical forms of arnebia euchroma extract and ANGIPARS
ointment and capsules, and were compared with each other and the control group. The clinical and statistical results
indicate the superior effect of oral and topical forms of arnebia euchroma extract in comparison with oral and topical
forms of ANGIPARS.The epithelial thickness(F (4.25) = 4189.10, p<0.01) and complete healing time(F (4.25) = 18.01,
p<0.01), were respectively calculated. It is recommended that a human study be conducted to determine the level of
blood glucose and its effect on TNFa and myeloperoxidase as the factors affecting tissue repair.
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| Keyword:
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Arnebia Euchroma; ANGIPARS; Diabetic Foot
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| EOI:
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-
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| DOI:
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https://doi.org/10.31838/ijpr/2019.11.03.015
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| Download:
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Request For Article
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