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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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URATE REGULATION GENE POLYMORPHISMS ARE CORRELATED WITH CLINICAL FORMS OF CORONARY HEART DISEASE

Author: , TASHKENBAEVA ELEONORA NEGMATOVNA, ZIYADULLAEV SHUKHRAT KHUDAYBERDIEVICH, KAMALOV ZAYNITDIN SAYFUTDINOVICH, TOGAEV DILSHOD KHIDIRNAZAROVICH, KADIROVA FARZONA SHUKHRATOVNA, ABDIEVA GULNORA ABDULLAEVNA
Abstract: Coronary heart disease is one of the most common cardiovascular diseases and a main cause of death and disability in the modern world. The roles of various external and internal factors in the etiology and pathogenesis of coronary heart disease must be established. The purpose of this study was to study the relationship of single nucleotide polymorphisms of the genes GLUT9 and URAT1 with coronary heart disease in the Uzbek population. The results of our study showed the importance of the polymorphic variants of URAT1 and GLUT9 in the genetic predisposition to coronary heart disease among the Uzbek population.
Keyword: Heart Disease, Polymorphism, Single Nucleotide, Genetic Association Studies
DOI: https://doi.org/10.31838/ijpr/2019.11.03.032
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