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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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The Effect of Zinc Sulphate Mouth Rinse on Halitosis Compared With Chlorhexidine and Placebo Rinses:A Comparative Study

Author: MAHA AL–SAFFAR
Abstract: Aim: To assess the clinical effect of zinc sulphate as a mouth rinse on halitosis compared with chlorhexidine and placebo rinses. Patients and Methods: A total of 65 patients (35 females and 30 males) with halitosis divided into three groups; Group I: 25 patients treated by zinc sulphate (0.05%) mouthwash; Group II: 20 patients treated by chlorhexidine mouthwash; and Group III: 20 patients treated by placebo rinse and serve as control positive group. Results: Females were more affected by halitosis than males (53.8% females and 46.2% males) with highly association between intra–oral condition (periodontitis, gingivitis, carious tooth and coated tongue) and halitosis. The results also showed that there was no significant difference (p> 0.05) between pre–treatment mean of halitosis in all groups but there were highly significant differences between post–treatment mean of halitosis in all groups with a higher reduction in mean of halitosis in Group I, followed by Groups II and III respectively. The results also demonstrated that a higher percentage of side effects (90%) occurred in Group II patient compared with only 48% of side effects in Group I patients. Conclusion: Zinc sulphate (0.05%) mouth rinse showed a good clinical effect demonstrated by reduction in mean of halitosis with a lower percentage of side effect compared with chlorhexidine and placebo rinses.
Keyword: Halitosis, mouth rinse,badodour, oral condition and halitosis.
DOI: https://doi.org/10.31838/ijpr/2019.11.04.040
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