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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Use of formalin as an immunostimulant in animal immunization to produce specific serum precursors

Author: POPOV VYACHESLAV, BAKHRIEV IBRAHIM, CHORIEV BERUNIY, HASANOVA MUKARRAM, AKHMEDOV TULKIN
Abstract: Immunostimulating property of formalin in the course of immunization of animals in obtaining specific precipitating high titre serum to determine the type of blood is experimentally established. The article presents the results of a comparative study of the adjuvant activity of 1%, 5% and 10% formalin solution in a mixture with human and animal blood serum. It is established that 10% formalin solution in the mixture with serum had the best adjuvant properties. Introduction of 10% formalin and blood serum solution into the mixture by animals contributed to obtaining immune serum precipitation suitable for use in forensic medicine.
Keyword: immunization, adjuvants, antigens, serum precipitating antigens.
DOI: https://doi.org/10.31838/ijpr/2019.11.04.066
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