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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Specific activity of a new antiallergic ointment in the treatment of contact allergic dermatitis

Author: KHATAMOV KHAYRULLA, SUYAROV AKRAM, ZIYADULLAEV SHUKHRAT, KIREEV VADIM, MUKHTOROV SHERZOD, ALIMZHANOVA LOLA
Abstract: In this paper, we studied the results of the effectiveness of the ointment isolated from a new thick extract of the sum of flavonoids from local raw materials on a hydrophobic basis in an experiment on Guinea pigs with allergic contact dermatitis caused by 2,4-dinitrochlorobenzene. The results of the study showed that 5 % ointment drug based on a thick extract of the sum of flavonoids, more effectively reduces the skin folds compared to 1%, 3% ointment based on a thick extract of the sum of flavonoids and antihistamine psilo-balsam and celestoderm'sglucocorticosteroid ointment. When analyzing the measurement of local temperature, the temperature in the 4-group of animals began to approach the initial level earlier than in other groups of experimental animals.
Keyword: atopic dermatitis, sums of flavonoids, Bidenstripartita, ointment, contact allergic dermatitis.
DOI: https://doi.org/10.31838/ijpr/2019.11.04.067
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