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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Metoprolol succinate as selective drugs for treatment of hypertension in pregnancyas bi layer floating tablet: a review

Author: SREEDHAR DAS, DR BIBHUTI BHUSANPANIGRAHI, DR MANOJKUMAR.PANI
Abstract: The review based upon characteristics ofMetoprolol Succinate and its implementation in treatment of hypertension in pregnancy as a form of Bilayer floating tablet.This review is prepared by focusing onhypertension during pregnancy, characteristics study of Metoprolol succinate and fulfilment of acceptance criterias ofBilayered floating tablet. Antihypertensive Metoprolol succinate is the ß1 receptor blocker .It can be implemented in case of pregnancy and lactation as a combined formwith other drugs in empty stomach .As bi layered floating tablet Metoprolol Succinate can act as sustained release layer and improve the controlled delivery of drug for prolonged period of time at stomach region by maintaining proper floating lag time and total floating time as bouncy study and improve the bioavailability and maintains consistency at entire sustained period.
Keyword: Metoprolol Succinate, Antihypertensive , Bilayered floating tablet
DOI: https://doi.org/10.31838/ijpr/2019.11.04.025
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