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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Pathogenic bacteria associated with acute childhood diarrhea and their susceptibility profiling in Misan Province, Iraq

Author: NOORALDEN JASIM, DIANA BASIM ABDULHAMEED AL-QAYSI
Abstract: Diarrheal disease is a major health problem causing death among children, especially, under 3-years of age, hence, it is necessary to detect the etiological agent for the active therapy of the disease. Two hundred stool specimens were collected from children with acute diarrhea between 2-60 months of age during April to October in 2018 from two hospitals in Misan Province. Diarrhea was more frequent in children with the age group (13-24 months) and the feeding bottle (64% and 63%, respectively). Pathogenic bacteria were presented in 56% of specimens. Enteropathogenic bacteria were identified by Vitek system. Out of 112 bacterial isolates were identified, E. coli was the common cause with 89 isolates. Nevertheless, the frequencies of Salmonella typhi , Shigella flexneri , Shigella sonnei and Shigella dysenteriae were 8, 5, 4 and 2 respectively, whereas, Salmonella enterica, Salmonella paratyphiA , Pseudomonas aeruginosa and Klebsiella pneumoniae were 1 for each. Antibiotic susceptibility tests accomplished onto identified isolates using the disc diffusion technique. Among the antibiotics tested, imipenem was a very effective drug (98.2%), followed by ciprofloxacin, co-trimaxazole and amikacin (77.6%, 76.7% and 61.6% respectively) ,while ampicillin and cephalothin were poor activity against the bacterial isolates (2.7% and 0.89%) respectively.
Keyword: Diarrheal disease; children; pathogenic bacteria; antimicrobial susceptibility.
DOI: https://doi.org/10.31838/ijpr/2019.11.04.102
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