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Evaluation of the Effects of Valeriana of Ficinalis Hydroalcoholic Extract on the Morphology of Cerebral Hippocampus Astrocytes in Rats
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| Author:
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ASGHAR HEIDARIAN, HAMDOLLAH DELAVIOZ, AMROLLAH ROOZBEHI*
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| Abstract:
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Parahypocamp and hippocampus are old regions of the cortex. Limbic system on different aspects of emotion and
behavior, including fear, anger, and feelings of sexual acts affect. The hippocampus is also involved in short-term
memory. The scientific name valerian officinalis valerian plant native to Europe, Asia and North America. The dried
root of this plant, oil extracts obtained in the treatment of sleep disturbances, depression and muscle relaxation to
reduce stress. In this study, is checked the effects of valerian hydroalcoholic extract on morphology of astrocytes in
hippocampus of the rats brain.40 Sprague dawley rats, were randomly divided into four group received distilled water
and group testing one, two and three with 300,400,600 mg extract daily; except Friday, by oral gavage for three
weeks and on the tenth day, were tested. Brain tissue samples fixed with conventional testing methods provided and
checked the size and number of astrocytes with olympus microscope. And the data collected were analyzed with spss
software. As this study was, hydro alcoholic extract of the valerian plant, at the doss studies , had efficacy in
increasing the number and reduction of large diameter of astrocytes of Hippocampus of rats brain. It also increases
the amount of extract increases its efficacy has been studied in more groups.
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| Keyword:
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Valerian plant, Hippocampal, Astrocytes, Rat
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| EOI:
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| DOI:
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https://doi.org/10.31838/ijpr/2020.12.01.019
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| Download:
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