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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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The Diagnostic Test of Ag-TB Rapid Test on Pulmonary Tuberculosis

Author: INAYATI , ANA MAJDAWATI, SURYANTO
Abstract: Currently, a rapid test for the detection of a specific secretion of D1, RD2, RD3 antigen of M. Tuberculosis (Ag-TB Rapid Test) in clinical specimens for Pulmonary Tuberculosis diagnosis has been developed. The aims of this study are to determine the sensitivity and specificity of Ag-TB Rapid Test toward the combination of microscopic Acid Fast Bacilli examination and chest radiography. One hundred outpatients with clinical pulmonary Tuberculosis were examined with the Acid Fast Bacilli (AFB) Microscopy, chest radiography and serology of Rapid test Ag-TB to determine sensitivity and specificity applying diagnostic test. The sensitivity and specificity are 43.7% and 76.2% respectively, and the combination of microscopic Acid Fast Bacilli examination and chest radiography are 38.5% and 98.5%. In conclusion, Rapid Test Ag-TB cannot be used to substitute the combination of microscopic Acid Fast Bacilli examination and chest radiography for early diagnosis of Pulmonary Tuberculosis.
Keyword: Ag-TB Rapid Test, diagnosis test
DOI: https://doi.org/10.31838/ijpr/2020.12.01.174
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