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Antioxidant Potential of Aqueous Extract of Entire Plant of Uraria Picta Desv.
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UPLOADED BY-ADMIN, BHARATKUMAR D PATEL, YOGESH H KAMARIYA, MANDEV B PATEL
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| Abstract:
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The plant Uraria picta desv.(Fam. Papilionaceae) a suffruticose sparingly branched perennial herb. Traditionally, the
plant is used as an antidote to the venom of a dangerous Indian snake, leaves are antiseptic and used against gonorrhoea. The
fruits, pods are effective against oral sores in children, roots are being used against cough, chills, fever. The main objective of
the present study is to access the antioxidant potential of aqueous extract of Uraria picta desv. The different in-vitro models
were studied for its free radical scavenging property viz. DPPH radical scavenging assay, ABTS radical scavenging assay, Ophenanthroline
assay, lipid peroxidation assay, superoxide scavenging assay, total antioxidant and non-enzymatic
haemoglobin glycosylation assay. The results were analyzed statistically by regression method. Its antioxidant activity was
estimated by IC50 value and the values were 152 µg/ml (DPPH radical scavenging), 112 µg/ml (ABTS radical scavenging),
29.31 µg/ml (O-phenanthroline assay), 86.39 µg/ml (lipid peroxidation), and 23.87 µg/ml (superoxide scavenging). Total
antioxidant capacity of aqueous extract of Uraria picta desv.(10mg/ml) is equivalent to 44.81 mg/ml of ascorbic acid. It
showed 74.54% inhibition in non-enzymatic haemoglobin glycosylation assay. In conclusion, significant antioxidant activity
was associated with presence of phenolic, flavonoid, sterol and terpene derivatives.
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DPPH, ABTS, lipid peroxidation, Uraria picta, Papilionaceae.
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