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Molecular Characterization of Iraqi Gumboro virus strains and Designing of B epitopes Vaccine
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| Author:
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AAISHA B., BALQEES HASSAN ALI, ZAHRA M. AL-KHAFAJI
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| Abstract:
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ntroduction: Gumboro disease is an infectious disease caused by Infectious Bursal Disease Virus treated by
vaccination of different types of vaccines with different regimes causes heavy losses to poultry industry. The
virus attaches lymphoid organs and leads to depletion of antibody producing immature B lymphocyte. Most
vaccines are failed in disease prevention due to emergence of very virulent strains. It is worldwide distributed
including Iraq.
Aims: Designing new vaccines depends on envelope protein epitopes
Results: Four B epitopes derived from the variable region of the virus envelop protein (VP2),
1
. These were
selected among 9 designed epitopes.
Conclusion: These epitopes were satisfied the required characters for B epitopes and waiting for wet lab
applications with different designed usage.
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| Keyword:
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Gumboro Disease, Iraq, B-epitopes, Vaccine Design, Immunoinformatic.
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| EOI:
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-
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| DOI:
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https://doi.org/10.31838/ijpr/2020.12.02.0147
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| Download:
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Request For Article
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