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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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A Contemporary Study on Recommending Outline of Antiepileptic Drugs

Author: NIRAJ SINGH, JEETENDRA KUMAR GUPTA
Abstract: Epilepsy is considered as episodic disorder that is caused by excessive, repeated and hyper-synchronous irregular electrical activity of brain neurons. In the course of treatment, inappropriate use of antiepileptic drugs may result in decreased quality of life, increased morbidity and mortality. The systemic assessment and appropriate prescribing pattern of antiepileptic agents may greatly assist health care professionals in rational prescribing. Questionnaire based survey was carried out to determine the attitude of physicians towards prescribing pattern of antiepileptic drugs. The present study was performed in the hospitals and clinics with the help of physicians and medical supporting staff for one year of time period. The findings were collected, tabulated and analyzed. Data were collected for 297 patients, out of which 15 (5.05 %) patients were infant, 130 patients (43.77 %) under middle age group (children) and 152 patients (51.17 %) adult. The drugs like Sodium valproate and carbamazepine are the commonly prescribed drugs in all age group of patients, in which Sodium Valproate was first choice of drug for all kind of seizures. Observations of the present study reveal that tonic clonic seizure (61.95%) was very common in this region of Utter Pradesh. It was also found that prevalence of tonic clonic seizure (61.95 %) was more common in this region. Mono therapy accounts for 97.31 % where as combination therapy 2.69 % was seen only in the case of the failure of mono therapy. In case of female patients, physicians used to prescribe folic acid with anti epileptic drugs.
Keyword: Epilepsy, Anti-epileptic drugs, prescribing pattern.
DOI: https://doi.org/10.31838/ijpr/2020.12.03.053
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