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Nanomedicine as an Emerging Treatment Approach for Many Cancers: An Updated Review
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| Author:
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SALIM M.,
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| Abstract:
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Cancer therapy has been greatly improved during the last years. Although curative treatments have been discovered for some malignant tumors, there still many challenges facing most of the conventional chemotherapeutics. Nanotechnology is being utilized for achieving a new generation of cancer therapeutics/theranostics recognized as nanomedicines characterized by having high sensitivity and selectivity for tumor cells. The increasing number of nanoformulations and nanomedicines that were approved by the US Food and Drug Administration is encouraging. The major obstacles on these new nanomedicines are the potential toxicity of the nanoparticles, which necessitate rigorous assessment before being utilized as cancer therapeutics. This review threw the light on some properties of nanocarriers and challenges facing the application of nanomedicines in the clinical practice. It also highlighted the recent application of nanomedicines in the treatment of many cancers and malignancies. It also summarized some future directions for investigating nanomedicines in both basic research and clinical studies.
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| Keyword:
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Nanomedicine, nanoformulations, nanocarriers, cancer, toxicity, liver, microenvironment.
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| EOI:
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-
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| DOI:
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https://doi.org/10.31838/ijpr/2020.12.03.105
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| Download:
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