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Detection of bla OXA-51-like and bla VIM Carbapenemase Genes in Acinetobacter baumannii isolated from burn patients
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| Author:
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SAFAA KADOM, INTIDHAAR N. ABID
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| Abstract:
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Carbapenemase producing bacterial pathogens causes of serious hospital acquired and community infections that are difficult to treatment and mortality rates associated with these infections are very high, because their emergence in multidrug resistant bacteria such as Acinetobacter baumannii , this study was aimed to detection some carbapenemase genes that include bla OXA-51-like and bla VIM in Acinetobacter baumannii isolated from burn patient infections , it was identified 20 isolates of Acinetobacter baumannii from burn patient infections in Al-Hussien teaching hospital and other burn care units in Al-Nasiriyah city from August / 2018 to February /2019 . It was founded that, all isolates were resistant (100%) to cephalothin and chloramphenicol, but 95% of A.baumannii were resistant to ticarcilin and pipracilin , and 90% of isolates were resistant to cefotaxime ,gentamicin , trimethoprim /sufamethaxazole and ceftriaxone. Bacterial isolates were registered lower resistance to colistin (45%).All isolates (100%) were appeared MDR bacteria that resistant to 3 classes of antibiotics that were distributed of 1(5%), 1(5%), 3(15%) , 2(10%) and 1(5%) of isolates were resistant to 3,4 , 5 ,6 and 7 respectively . It was also demonstrated that , 3(15%) of isolates were extensive drug resistance (XDR ) and 9(45%) of A.baumannii were pandrug resistance (PDR). OXA-51 like gene were detected in all isolates (100%). The results showed that 13 isolates (65%) of A. baumannii were possessed bal-VIM gene.
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| Keyword:
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Acinetobacter baumannii , bla OXA-51-like , bla VIM ,Carbapenemase
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| EOI:
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| DOI:
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https://doi.org/10.31838/ijpr/2020.12.02.188
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| Download:
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