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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Serum Bicarbonate Level And Nutritional Status In Non-Diabetic And Non-Dialysis Stage 5 Chronic Kidney Disease Patients

Author: EKY RIYADI, NUNUK MARDIANA, WIDODO
Abstract: Introduction: Malnutrition is one of the common complication of Chronic Kidney Disease (CKD), although usually not diagnosed. This study analyzed the correlation of serum bicarbonate level and nutritional status in non-diabetic and non-dialysis stage 5 Chronic Kidney Disease patients. Methods: This was an observational cross-sectional study. Serum bicarbonate level was obtained from Blood Gas Analysis (BGA), and nutritional status was assessed using Subjective Global Assessment (SGA). Results: Forty non-diabetic and non-dialysis CKD stage 5 patients were enrolled in this study, consisting of 26 (65%) males and 14 (35%) females. The median age of this subjects was 52 years with range of 23-65 years. The mean serum bicarbonate was 14.2 ±3.89 mEq/L (range 6-22.4). Nutritional status of the subjects was divided into three groups, 8 patients (20%) were severely malnourished, 11 patients (27,5%) were mild-moderately malnourished, and 21 patients (52,5%) were well nourished. There was a significant correlation (r = -0.49; P = 0.001) between serum bicarbonate level and nutritional status. Conclusion: This study indicates that serum bicarbonate level was significantly correlated with nutritional status.
Keyword: Malnutrition, Chronic Kidney Disease, Serum Bicarbonate, Metabolic Acidosis
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