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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Utilization pattern of drugs in stroke patients in a tertiary care hospital

Author: AFIFA FATIMA, MOHAMMED FARHAN AHMED, SAFA AMREEN SALIM AWAD, SIDRAH FIRDOUS, NILOUFER ALI, ANITHA NANDAGOPAL
Abstract: Objective: Stroke otherwise known as Cerebrovascular accident (CVA) is one of the most leading causes of death and disability in the world. More than 100 per cent increase in the incidence of stroke in low- and middle-income countries including India from 1970-2008 had been reported. By identifying the risk factors of the disease, effectiveness of the therapy can be improved. Our study points out the risks and drug utilization in stroke patients. Methodology: A retrospective study was carried out on stroke patients in Aster prime hospital, Hyderabad for a period of 1 year from August 2018 to September 2019. Required demographic and laboratory data was analysed. Results: A total of 153 stroke patients prescription was analysed for drug utilization pattern. Out of 153 patients, 131 patients were of ischemic stroke and 22 were haemorrhagic stroke. The prevalence of stroke was higher in males (63%) compared to females (37%), with occurrence in the age group of 51-60. The most common risk factors associated with stroke was hypertension (65%) followed by diabetes mellitus (44%), coronary artery disease (10%). Polypharmacy was observed in 95% of prescriptions. To the stroke patients cerebral activators (11.72%) were prescribed maximum followed by antacids (9.25%), antiplatelets agents (8.84%), lipid lowering agents (8.63%) and antihypertensives (6.71%). Conclusion: Our study emphasises on the need of identifying the risk factors of stroke, providing awareness to the patients and thereby improving the effectiveness of the therapy. It also assesses the rationality in prescribing of drugs.
Keyword: Stroke, drug utilization, risk factors, hypertension, cerebral activators
DOI: https://doi.org/10.31838/ijpr/2020.12.03.054
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