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Efficacy of Oral Gabapentin For Attenuation Of Haemodynamic Responses To Laryngoscopy & Tracheal Intubation
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| Author:
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BHAVITHA VENIGALLA, SANJOT SUDHIR NINAVE, AMOL SINGAM, S.S. KHEDKAR
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| Abstract:
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Background: The major integral part of general anaesthesia is laryngoscopy and tracheal intubation. These will be and are the main stay for securing a definitive airway in anaesthetised patients. Inspite of its advantages it is not devoid of complications, it is capable of showing broad set of stress responses ranging from tachycardia, hypertension, increased intraocular and increase intracranial pressure, bronchospasm and laryngospasm due to profound sympathetic haemodynamic alterations called Pressor responses. There is a need for attenuation of these pressor responses caused by laryngoscopy and tracheal intubation. Various drugs like lignocaine (both i.v and i.m), adrenoreceptor blockers, narcotics, vasodilators, calcium channel blockers, So here in our study we consider the use of Oral Gabapentin 800 mg in attenuation of pressor responses.
Objectives: To study the efficacy of addition of oral gabapentin to fentanyl on the haemodynamic responses during laryngoscopy and endotracheal intubation
Methodology: After approval from ethical committee of the institution, 90 patients in a age group between 20 years to 60 years belonging to ASA Class I & II , who were willing to participate and scheduled to undergo various elective surgeries under General anaesthesia. Patients are divided into 2 groups, Group F and Group G ; Group F will be receiving fentanyl and Group G will be receiving oral gabapentin 800mg 2 hours prior to surgery and fentanyl prior to laryngoscopy and tracheal intubation.
Results: Group G are expected to show slightly a better attenuation of haemodynamic responses compared to group F. The side effects of Oral Gabapentin were also considered
Conclusion: The synergistic action of gabapentin & fentanyl helped attenuating the pressor responses due to laryngoscopy and tracheal intubation
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| Keyword:
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Oral gabapentin; pressor responses; Laryngoscopy; Tracheal intubation; and; attenuation; haemodynamic responses.
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| EOI:
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-
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| DOI:
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https://doi.org/10.31838/ijpr/2019.11.02.218
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| Download:
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