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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Comparative study of intravenous nalbuphine versus tramadol for postoperative analgesia in patients undergoing lower abdominal surgeries under subarachnoid block

Author: SANJOT NINAVE, AMOL SINGAM, Y.U. CHITRIV
Abstract: Background: The study is carried out for comparing the efficacy of Nalbuphine with Tramadol as a post-operative analgesic. Tramadol is used for moderate analgesia and it is a weak opioid, Nalbuphine, a new opioid which has antagonistic action at µ receptors and agonistic action at ? receptor. Methodology: In this study, sixty patients undergoing lower abdominal surgeries will be allocated into 2 groups of 30 each – group N and group T. Group N will be given Inj. Nalbuphine 0.1mg/kg IV Group T will be given Inj. Tramadol 1mg/kg IV We then compared the post-operative analgesia in both the groups along with the sedation score and side effects. Results: we hypothesize that nalbuphine is better than tramadol for postoperative analgesia Conclusion: When the result will come as expected then we came to a conclusion that nalbuphine is better than tramadol for post-operative analgesia and also nalbuphine causes less side effects when compared to tramadol when given intravenously.
Keyword: nalbuphine, tramadol, postoperative analgesia, lower abdominal surgeries
DOI: https://doi.org/10.31838/ijpr/2019.11.03.150
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