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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Efficacy of Platelet Rich Plasma (PRP) for the treatment of Ulcers over Foot

Author: SHIVANI KSHIRSAGAR, CHANDRASHEKHAR MAHAKALKAR, MEENAKSHI YEOLA (PATE), PRACHI PALSODKAR
Abstract: Background: An ulcer is a breach of the continuity of skin, epithelium of mucous membrane in the body which is caused by removal of necrotic tissue [1]. Foot ulcers may be caused by numerous medical conditions. The key to treatment is daily sterile dressing till the formation of healthy granulation tissue, infection control by appropriate use of antibiotics, surgical interventions such as debridement or amputation if needed. PRP is a concentration of huge volume of platelets in a small plasma volume. It is effective, biocompatible and safe [2]. Objectives: • To analyze the effectivity of Platelet rich plasma for the treatment of ulcers over the foot of all the etiologies. • Comparison the rate of wound healing in both the groups (In terms of percentage of reduction of wound at day 30). • To compare the length of hospital, stay and complications in both the groups. • To analyze the safety profile of PRP as a treatment modality for foot ulcers. Methodology: It is a randomized controlled trial, done on the patients with foot ulcer due to any cause. It will be conducted at Dept. of General Surgery, J.N.M.C and AVBRH, Sawangi (Meghe), Wardha.The study will be conducted on patients of foot ulcers. Informed consent will be obtained from all the patients and institutional ethical committee approval, DMIMS (DU) will be taken. Expected Results: At least 20% reduction in the wound size. This would be beneficial in cost reduction of treatment of foot ulcers. Conclusion: Conclusion will be based on findings for study of protocol.
Keyword: Platelet, PRP, ulcers
DOI: https://doi.org/10.31838/ijpr/2019.11.03.151
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