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Impact of platelet indices as prognostic markers of sepsis
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| Author:
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ANUSHA GUPTA, RAJESH SARODE, SUNIL KUMAR, GAURI MANOJ DHOPAVKAR
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| Abstract:
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Background: Sepsis can be defined as a life-threatening condition which is arising from the body's response to an infection. Septic shock is taken as a subset of sepsis in which there is intense circulatory and metabolic abnormalities. it is associated with higher risk of morbidity and mortality as compared to sepsis alone. Sepsis can also lead to dysfunction in multiple organs of the body leading to the so-called MODS. Platelet indices are routinely used blood tests however their application as prognostic markers in sepsis hasn’t been utilised fully. We intend to do the needful for it.
Objectives: Assess platelet indices like MPV, PDW, Platecrit as interpreters of in hospital mortality in Sepsis, to evaluate the effect of different platelet indices as prognostic markers of sepsis, to assess severity of sepsis by assessment of immature platelet function in bacterial infection.
Methods: The study is a prospective cross-sectional study, All the consecutive/sequential patients > 18 years of age, admitted to Medicine ICU in tertiary medical hospital. The severity for the sepsis is graded using the APACHE II scoring and diagnosis is done using the bedside q SOFA test.
Results: From the following study we will be able to correlate that platelet indices are useful to predict the prognosis in sepsis patients.
Conclusion: using the above study we can correlate platelet indices to in hospital mortality and severity of the disease. Patients with severe disease are thought to have reduced platelet count and other changes in platelet indices.
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| Keyword:
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Platelet Indices, Shock, Platelet Indices, Apache II, Sirs, Sepsis
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| EOI:
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| DOI:
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https://doi.org/10.31838/ijpr/2019.11.03.153
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| Download:
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