|
A Study on Analgesic Efficacy of Intrathecal Bupivacaine and Fentanyl with Intrathecal Midazolam for Lower Limb Surgeries.
|
|
| Author:
|
DEEPJIT BHUYAN, ARUNA V. CHANDAK, AMOL SINGAM, S.S. CHAUDHARI
|
| Abstract:
|
Background: Subarachnoid block is considered a safe regional anaesthesia technique. This technique is widely used for both elective as well as emergency surgical procedures. It is a good anaesthesia technique for surgeries like caesarean section, lower abdominal surgeries, lower limb orthopaedic surgeries and urological procedures.
Objectives: To evaluate the efficacy of intrathecal midazolam in potentiating the analgesic effect of intrathecal fentanyl along with a prolonged sensorimotor block in patients undergoing lower limb surgery.
Methodology: The present study is carried out in the Department of Anesthesiology, JNMC & Acharya Vinoba Bhave Rural Hospital, Sawangi (Meghe), Wardha after taking prior permission from institutional ethical committee. Randomized, prospective, case-controlled study. This study will comprise of 100 patients. They will be randomly allocated into two groups of 50 each. Group F (50 subjects) – intrathecally 3 ml of 15mg 0.5% hyperbaric bupivacaine + 25 mcg of fentanyl in 0.5 ml along with 0.2 ml 0.9% saline and Group M (50 subjects) – intrathecally 3 ml of 15 mg 0.5% hyperbaric bupivacaine + 25 mcg of fentanyl in 0.5 ml along with 1 mg of midazolam in 0.2 ml.
Results: We hypothesize that intrathecal midazolam would potentiate the effect of intrathecal fentanyl in terms of prolonged duration of analgesia and prolonged sensory and motor block without any significant hemodynamic compromise.
Conclusion: When the result will come as expected then we can conclude that concept incorporating intrathecal midazolam and fentanyl together for a prolonged duration of analgesia and prolonged sensory and motor block without any significant hemodynamic compromise.
|
| Keyword:
|
intrathecal, fentanyl, midazolam, analgesia, efficacy
|
| EOI:
|
-
|
| DOI:
|
https://doi.org/10.31838/ijpr/2019.11.04.511
|
| Download:
|
Request For Article
|
|
|