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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Relevance of the use of plant extracts in the creation of functional products that have a geroprotective effect

Author: ANNA VESNINA, ALEXANDER YU. PROSEKOV, ANASTASIA I. DMITRIEVA, LYUDMILA K. ASYAKINA, NATALIA S. VELICHKOVICH
Abstract: Increasing healthy lifespan is an urgent area of study in the modern world. But lifespan is negatively affected by age-related pathologies, which are expressed in the violation of various functions of the body, in the development of degenerative diseases (cancer, type 2 diabetes, obesity, cardiovascular diseases, etc.). a Balanced diet can support and improve the functioning of the body, that is, contribute to "healthy aging". In this work, an analysis was conducted of the literature in gerontology and nutrition by researching both domestic and foreign databases. As a result of the analysis, we studied diseases that contribute to aging, the concept of "healthy aging" and its components, and considered oxidative stress as an important factor in the occurrence of degenerative diseases. The priority role of nutrition in maintaining health and increasing life expectancy is highlighted. Among all the nutrients, the authors identified biologically active substances of plant origin, which were geroprotectors, that is, substances that protect the body from premature aging. These substances include (flavonoids, vitamins, carbohydrates, carbohydrates), the sources of which are plants: common yarrow (Achillea millefolium L.), common thyme (Thymus Vulgaris), Elmwood (Filipendula ulmaria), rose Rhodiola (Rhodiola rosea L.), Ginkgo biloba (Ginkgo biloba), garlic (Allium sativum L.), Siberian fir (Abies sibirica l). Biologically active substances extracted from plants can be systematically consumed in the form of dietary supplements or functional foods. Thus, the use of functional products enriched with geroprotectors is the best preventive tool for various degenerative diseases that negatively affect life expectancy.
Keyword: plant raw materials, gerontology, oxidative stress, healthy aging, functional product, geroprotectors, nutraceuticals, antioxidants.
DOI: https://doi.org/10.31838/ijpr/2020.12.03.261
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