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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Assessment of the content of heavy metals in medicinal plants of genus trifolium from the growing area on the example of the siberian federal district

Author: A. DMITRIEVA, O.V. BELASHOVA, S. A. IVANOVA, A.YU. PROSEKOV, I. S. MILENTEVA
Abstract: Along with the examining biologically active organic compounds contained in plants, it is important to determine the biological role of elements in plants, and especially the elemental composition of medicinal species that grow in areas with adverse environmental conditions. Until recently, medicinal plants have not been studied in this aspect, because they did not cause social concerns and were not the objects of environmental problems. However, recently the anthropogenic impact on the environment has become more diverse and significant. Given the prospective introduction of plants of the genus Trifolium into scientific practical medicine, the safety of using this resource becomes an extremely urgent task. This work is devoted to the determination of heavy metals in medicinal wild plants Trifolium in various places of growth and the influence of the sample preparation method on the determination of heavy metals in medicinal plants. It was found that for sample preparation of Trifolium plant raw materials for the content of heavy metals by inversion voltammetry, it is more appropriate to use wet salting with sulfuric acid. The examination of 22 Trifolium samples obtained in various growing areas for the content of heavy metals was carried out. It was found that the content of heavy metals does not depend on the place where Trifolium grows, but depends on the type of Trifolium. So T. repens L. accumulates the maximum amounts of calcium, manganese, molybdenum, and cobalt. T. montanum L. accumulates the maximum amount of iron, copper, nickel, phosphorus, manganese, and chromium. T. repens L.accumulates iron, copper, nickel, phosphorus, chromium, and magnesium. T. hybridum L., as well as T. aureum Poll. on the contrary, they accumulate only a minimal amount of chemical elements: calcium, magnesium, strontium and chromium in T. hybridum L. and iron in T. aureum Poll. T. pratense L. contains the maximum amount of strontium, and the minimum amount of potassium, phosphorus, silicon, manganese, nickel and molybdenum. T. lupinaster L contains potassium and silicon in the maximum amounts compared to other species, and copper and cobalt in the minimum values. A high content of elements such as zinc, sodium, boron, and barium was observed in all the samples studied. The lowest concentrations are found in cobalt, cadmium, molybdenum, selenium, tin, lithium, silver, and antimony.
Keyword: heavy metals, Trifolium, voltamperometry, toxic metals, medicinal plants, technogenic pollution.
DOI: https://doi.org/10.31838/ijpr/2020.12.03.262
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