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Age-Associated Changes to Face Skin in the Context of Change of its Morphological Structures (Review).
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| Author:
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OLGA OSIPOVA, YURIY A. MEZENTSEV, ALEXEY R. SHABALIN, LILIA A. KRUPENKINA, YURIY A. HOSHENKO
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| Abstract:
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The average age of the population must meet the requirements for maintaining health, as they lead an active lifestyle and take care of themselves. The main visual indicator is the condition of the skin and body as a whole. This article is devoted to the features of the anatomical and physiological models of biological aging of various layers of the skin.
The skin, as well as any other organ system, is subject to both internal (chronological) and external (environmental) aging. External factors include the action of solar radiation, causing the so-called "photoaging", polluted air, smoking, etc. Early skin aging is mainly due to chronic exposure to ultraviolet radiation. Chronological aging is programmed in the genetic background and is time-dependent. Numerous mechanisms are involved in age-related skin degradation, and they are also associated with non-healing or chronic wounds in the elderly. In particular, the generation of reactive oxygen species plays an important role in age-related skin modifications. This article will present data on age-related skin degradation.
The skin provides primary body protection and plays an important role in maintaining overall homeostasis. Signs of growing skin have such signs as wrinkles, loss of elasticity and firmness, rough appearance. The aging process is accompanied by phenotypic changes in the skin cells, as well as structural and functional changes in the components of the extracellular matrix, such as collagens, glycosaminoglycans and elastin. The extracellular matrix, which gradually changes with age, affects the normal structure of the structure and its ability to recover.
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| Keyword:
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Skin aging, aging of skin structures, age-associated changes in the face, signs of aging.
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| EOI:
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-
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| DOI:
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https://doi.org/10.31838/ijpr/2020.12.02.203
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| Download:
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