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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Synthesis a novel nano co-polymer and using as carrier drug system

Author: AMEL HASAN, MOHAMMAD N. AL-BAIATI, MOHANAD M. KAREEM
Abstract: In this work, a novel nano co-polymer was prepared from the reaction of phthalic anhydride with glycerol, as it was diagnosed by the infrared spectroscopy and the XRD technique. This nano co-polymer has been linked to five types of drugs (Amoxicillin, Cefalexine, Ampicillin, Mefenamic acid and Ciprofloxacine), and it was diagnosed by the infrared spectroscopy. The release of the drug from its binding to the nano co-polymer was performed, and it showed distinguished results in the release process in the basic medium (pH= 8.8).
Keyword: Amoxicillin, Cefalexine, Ampicillin, Mefenamic acid, Ciproflexase; Co- polymer; Nano co-polymer, carrier drug system, Swelling.
DOI: https://doi.org/10.31838/ijpr/2020.12.04.120
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