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Tissue Engineering in Oral and Maxillofacial Surgery - A Literature Review
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| Author:
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KALYANI.P , M.P.SANTHOSH KUMAR
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| Abstract:
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The reconstruction of maxillofacial defects post trauma or post surgery is a challenging aspect of oral and maxillofacial surgery. Tissue engineering is that discipline that combines principles of biochemistry, cell culture and engineering to produce biocompatible tissues. The principle of tissue engineering involves a triad of scaffold, cell lines and signalling molecules. A variety of tissues such as bone, mucosa, skin, fat, muscles, nerves, salivary glands and skin have been cultured by researchers. Of these, the regeneration of bone using tissue engineering has proved to be successful and is currently used for maxillofacial reconstruction. There are a number of case reports that have revealed the use of tissue engineered bone grafts in maxillomandibular reconstruction and ridge augmentation procedures to be successful. The vascularization of such tissue engineered grafts is of particular importance and is carried out in vitro or in vivo. The success of this technique largely relies on the correct selection of tissue engineering components, skillful operator and adequate vascularization. The review focuses on the components, current concepts and challenges in tissue engineering, supported by case reports on reconstruction using tissue engineering.
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| Keyword:
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Tissue, Maxillofacial, Literature
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| EOI:
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| DOI:
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https://doi.org/10.31838/ijpr/2020.12.01.309
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| Download:
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Request For Article
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