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Renal Impairment in Diabetes Mellitus Type2 In Iraq
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| Author:
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ALAA ABDULJABBAR ABDULRAZZAQ
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| Abstract:
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The present study was designed to investigate if there is any relation of inflammatory markers in the development and progression of renal impairment in diabetes mellitus type 2, so this study was conducted in the department of Biology, Al-Rasheed University College, comprising of n= 80 subjects known Diabetes mellitus patients with an age range 30 - 60 years and healthy controls n=80 with age range 30 - 60 years attending the national diabetes center for treatment. The study was aimed to quantitatively estimate the amount of serum urea, creatinine and IL-6 levels present in the blood, and evaluate their correlation in diabetic and non-diabetic subjects. The mean (± S.D.) serum urea level in the control group was found to be 24.95±10.88. whereas in diabetics, it was found to be 50.75±19.69. The mean (± S.D.) serum creatinine level in the control group was found to be 0.81±0.14 whereas in diabetics, it was found to be 1.40±0.87. The Il-6 in the control group was found to be 7.41 + 0.54 whereas in diabetes patient 10.66 + 1.16 thus, the mean levels of urea, creatinine and Il-6 was significantly higher in the diabetic subjects as compared to controls. So, the urea and creatinine and Il-6 is simple and useful biomarker which can serve as predictor tests for assessing kidney functions (nephropathy) in diabetic patients type2.
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| Keyword:
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Interleukin-6 (IL-6), urea, creatinine, ELISA, Diabetes mellitus, Biomarker, nephropathy, fasting blood glucose
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| EOI:
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-
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| DOI:
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https://doi.org/10.31838/ijpr/2020.12.01.329
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| Download:
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Request For Article
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