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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Seratiopeptidase vs methylprednisolone in the reduction of pain after the extraction of mandibular third molar

Author: HARINI G, DR.DINESH PRABHU, DR.BALAKRISHNAN R N
Abstract: Surgical removal of mandibular third molar result in some degree of post operative pain,swelling.They can be controlled by proper administration of local anesthesia,careful bone removal,minimal trauma to soft tissue and administration of drugs.The aim of present study was to compare the efficacy of methylprednisolone and serratiopeptidase in controlling postoperative pain,swelling and trismus.The total of 50 patients were divided into two groups of 25 patients in each undergoing surgical removal of mandibular third molar .Group A was given with prednisolone and group B was given seratiopeptiosole daily.The result showed prednisolone is an effective analgesic while serratiopeptidase has moderate analgesic activity .Methylprednisolone is more effective than serratiopeptidase is in controlling post surgical pain. We conclude that prednisolone affords better relief than serratiopeptidase
Keyword: Prednisolone, Seratiopeptisole, Pain, Swelling, Trismus.
DOI: https://doi.org/10.31838/ijpr/2021.13.01.193
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