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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Retrospective Study to Analyze Prevalence of Intravenous and Oral Antibiotics in Space Infection

Author: , AMINA MEHRIN BANO, HEMAVATHY O.R, SRIRENGALAKSHMI
Abstract: Aim: The aim of this study was to analyze the prevalence of IV and oral antibiotics in space infection in a university dental hospital in South India , Chennai . Background: Odontogenic infections are among the most common infections of the oral cavity. They can be caused by the sequelae of dental caries, periodontal disease or due to trauma. Early recognition and management of acute orofacial infection is critical because of rapid systemic involvement. Therapeutic antibiotics are advised to treat infections in the oral cavity after local debridement has failed, whereas prophylactic antibiotics are given to prevent disease caused by oral flora, introduced to different sites , which puts the host at risk If antimicrobial therapy is advised soon after diagnosis and before surgery, it can shorten the period of infection and minimize associated risks such as bacteremia. Materials and methods: Patients reporting with pain, swelling, and infection were included in the study. Their treatment whether extraction, RCTs or incision and drainage were followed and antibiotics prescribed was recorded. data collection was done using DIAS , tabulated using EXCEL and analysed using SPSS. Results: The study population included males 58.3% and females 41.6%, out of which a higher incidence of space infection was reported in males. In the limits of our study the oral route of prescription seemed to be higher, 60%. It was also reported that the highest prescribed antibiotics was amoxicillin and its combination, Augmentin, 25% and 50% respectively. Most common infection was the buccal space infection (58.3% ). The frequency of antibiotics prescribed was amoxicillin 25%, clindamycin 8.3%, metronidazole 16.7% and Augmentin 50% Conclusion: Antibiotics should be judiciously used only when indicated. Amoxicillin continues to be the drug of choice used in infections with odontogenic origin . The severity of the disease warrants the different routes of administration. The oral routes of prescription have a higher incidence in the limits of our study population.
Keyword: Space infection; prevalence; antibiotics prescribed ; frequency ; IV route ; oral route;
DOI: https://doi.org/10.31838/ijpr/2021.13.01.227
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