*Five Years Citation in Google scholar (2016 - 2020) is. 1451*   *    IJPR IS INDEXED IN ELSEVIER EMBASE & EBSCO *         Journal is Currently Not Indexed in Scopus as on february 2021 list Updated by scopus

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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Effervescent Tablet Formulation and Physical Evaluation of Gong-Gong Shell Waste (Strombus turturella)

Author: , SUCI FITRIANI SAMMULIA, HASYRUL HAMZAH, CHAERUL FADLY MOCHTAR, AMELINDA OKTAVIANI
Abstract: The gong-gong snail (Strombus turturella) is a type of sea snail commonly found around Bintan Island, Riau Archipelago. It is a culinary tour of the typical food of the Riau Islands. This food produces shell waste that is not used correctly. The main composition of gong-gong shells is calcium carbonate (CaCO3), which is very good for preventing osteoporosis. With the presence of calcium, the waste of gong-gong shell can be used as a raw material for the manufacture of pharmaceutical preparations that are effective, efficient, and have high aesthetic value. This study aims to obtain a formulation of effervescent tablets from the waste of gong-gong shells with a variety of active substances and good physical properties. Effervescent tablets were made by wet granulation method in 3 formulas with various concentrations of FI (15%), FII (30%), and FIII (45%) at the concentration of gong-gong shells. The resulting granules and tablets were evaluated. The results of the granule evaluation show that the granules produced from the three formulas meet the requirements. The tablet evaluation results showed that the organoleptic test, weight uniformity, size uniformity, hardness, and pH of the three formulas had met the requirements of a good effervescent tablet. While the three formulas did not meet the brittleness test requirements, the dissolving time test of F III did not meet the requirements. The results of this study indicate that the shells of the gong-gong can be formulated into effervescent tablets and have good physical properties.
Keyword: Effervescent Tablets, Gong-Gong Snail, Strombus turturella, Shell Waste
DOI: https://doi.org/10.31838/ijpr/2021.13.01.552
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