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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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A Detailed Review on Drug Delivery Technologies for the Management of Brain Tumour

Author: ARUN K, ARUN RADHAKRISHAN
Abstract: Nanotechnology is a multidisciplinary d0omain which has provoked a significant impact on clinical medicine. Throughout the years nanotechnology has evolved in various aspects rendering multiple applications in the field of pharmaceutical development and overcoming the problems of conventional techniques. Nanotechnology has already acquainted with oncology facilitating the treatment of tumours. Nanotechnology posses various characteristics like preferential accumulation of chemotherapeutics in tumour, low distribution in normal tissues, pharmacokinetics, biodistribution and clearanceproviding improved diagnosis and tumour treatment. Though the field of oncology developed massively, limitations still exists in treating neuronal tumours due to intricate structure of the blood–brain barrier. Nanotechnology with its feasibility to attachvarious molecules on their surface and transform them into excellent transport vehicles with ability to cross cell and/or tissue barriers, including the BBB. This review elaborately delivers the techniques and strategies used to improve the diagnosis and to treat neuronal tumours unlike conventional cancer therapies.
Keyword: Nanotechnology, neuronal-onco therapy, brain tumours, glioblastoma, liposomes
DOI: https://doi.org/10.31838/ijpr/2021.13.01.602
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