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Humanistic Outcome Assessment of Type 2 Diabetes Mellitus Patients: A Prospective Study
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| Author:
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SADAGOBAN G K, S PREETHA, ANGELA ABRAHAM EDAYADI, SWATHI SWAROOPA BORRA, AYILYA M, ARUN KANNIYAPPAN PARTHASARATHY
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| Abstract:
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Objectives: Understanding and measuring the patient’s perception on type 2 diabetes mellitus (DM)
treatment’s and its related health outcomes are important for developing type 2 DM treatment strategic
choices which helps clinicians to make appropriate decisions and benefit the patients.
Methods: In this context we conducted a study on type 2 DM patients (n=68) using the translated and
validated Diabetes Symptoms Check list -revised (DSC-r) (Tamil Version) Scale for measuring the patient’s
perception on type 2 DM treatment options. Selected type 2 DM patients were categorized based on their
oral hypoglycemic regimens such as, Metformin with Glipizide (M+ GP), Metformin with Glibenclamide
(M+GB) and Metformin (M). DSC-r 34 items self-administering questionnaire was used to measure the type 2
DM patients HRQoL status on 8 major type 2 DM symptom domains such as cardiology, neurology,
ophthalmology, psychology, hypoglycemia, hyperglycemia, fatigue, pain.
Results: The DSC-r Mean Dimensional Score (MDS) were identified and it was found to be 1.97896 for M
+GP treated group, 2.06448 for M+GB treated group and 1.96597 for M treated group.
Conclusions: Humanistic outcome analysis results showed that all the three anti-diabetic regimens produced
only partial health status with the quality-adjusted life-year (QALY) average of about 0.60/Year.
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| Keyword:
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Pharmacoeconomics, Type 2 Diabetes Mellitus, Humanistic Outcome, Health Related Quality of Life, Burden of Disease
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| EOI:
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| DOI:
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https://doi.org/10.31838/ijpr/2021.13.02.124
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| Download:
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