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A Thorough Review Of Bioanalytical Method Developed For The Estimation Of Diclofenac In Biological Fluids
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| Author:
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, BALA SUNDARAM MURALITHARAN, NAGARAJAN JANAKI SANKARACHARI KRISHNAN, BHUVANESHWARAN ANANDAMOORTHY, ANBU KANNAN, APARNA SEBASTIAN
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| Abstract:
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Diclofenac is an anti-inflammatory non-steroidal drug used in the treatment of pain and inflammatory disorders
like gout and rheumatoid arthritis. It functions by reducing prostaglandin and COX-I & II blocks. Several
methods for estimating diclofenac sodium in biological samples have been developed and validated. Many
papers have been published regarding the analysis of diclofenac in pharmaceutical formulations as well as in
biological fluids. This article addresses different analytic approaches using a range of biological matrices,
including liquid chromatography-tandem mass spectrometry, high-performance liquid chromatography, and gas
chromatography. We have collected the article and reviewed the analysis of diclofenac in biological fluids.
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| Keyword:
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Bioanalytical, diclofenac, method development, plasma, HPLC, LC-MS.
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| EOI:
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| DOI:
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https://doi.org/10.31838/ijpr/2021.13.02.216
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| Download:
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Request For Article
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