*Five Years Citation in Google scholar (2016 - 2020) is. 1451*   *    IJPR IS INDEXED IN ELSEVIER EMBASE & EBSCO *       

logo

INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
ISSN
0975-2366
Current Issue
Article In Press
No Data found.
ADOBE READER

(Require Adobe Acrobat Reader to open, If you don't have Adobe Acrobat Reader)

Index Page 1
Click here to Download
IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

Click to download
 

Article Detail

Label
Label
New Method Development to Isolate Andrographolide Compound from Andrographis Paniculata (Burm. F) Nees Using Al2O3

Author: , KURNIA RAHAYU PURNOMO SARI, NOFRAN PUTRA PRATAMA, RIZQA SALSABILA FIRDAUSIA
Abstract: This study aimed to determine the effect of using Al2O3 active neutral in the process of andrographolide isolation from Andrographis paniculata. The extraction of Andrographis paniculata herbs was carried out with ethanol solvent. Isolation of andrographolide was continued using non-polar solvent, then passed to Al2O3 column and eluted with methanol. Next, the purification of isolated crystal was obtained by recrystallizing the extract using cold methanol. Identification of the isolated crystal was confirmed qualitatively by an analysis of the melting point, TLC, and FTIR spectra. The data obtained then compared with an analytical grade of andrographolide as the standard. The results showed that the data of isolated crystal was similar to the andrographolide standard from the parameter of melting point, TLC analysis, and FTIR spectra. From this research is known that isolation of andrographolide using Al2O3 could be an alternative method which more efficient and less solvent. In conclusion, this method is potentially developed as one of the methods to isolate andrographolide compounds from Andrographis paniculata
Keyword: andrographolide, Al2O3, isolation, characterization
DOI: https://doi.org/10.31838/ijpr/2021.13.02.255
Download: Request For Article
 




ONLINE SUBMISSION
USER LOGIN


Username
Password
Login | Register
News & Events
SCImago Journal & Country Rank

Terms and Conditions
Disclaimer
Refund Policy
Instrucations for Subscribers
Privacy Policy

Copyrights Form

0.12
2018CiteScore
 
8th percentile
Powered by  Scopus
Google Scholar

hit counters free