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Nitrosative Stress and Type 2 Diabetic Patients
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| Author:
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, ABDULLAH ALI MOHAMMED, AHMED JASIM NAWFAL, AHMED TALIB YASSEN ALDOSSARY, AULA H.OBAID
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| Abstract:
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The death of mammalian cells causing diabetes mellitus is linked to nitrosative stress rates (DM). Through all
antioxidant enzyme pathways (SOD, CAT, GPx, GSH) and full oxidative capacity (TAC) that cause
peroxidative destruction of carbohydrates, proteins, lipids, and nucleic acids that could be used as DM
biological markers, both forms 1 and 2 DM involve major oxidative and nitrosative stress coupled with severe
changes. Many cardiovascular events, including obesity, hyperlipidemia, diabetes, hypertension, and impaired
glucose metabolism, describe Metabolic Syndrome (MS) as a global public health problem. Oxidative damage
and cellular redox imbalance are the relationship between MS and related diseases, all related to the existence
of chronic inflammatory conditions that classify MS. Oxidative (nitrosative) stress-induced consequences of
diabetes, including stroke, neuropathy, retinopathy, and nephropathy. The association between type 2 diabetes
and oxidative or nitrosative stress is discussed in this review.
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| Keyword:
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Nitrosative stress, Metabolic syndrome, Pathogenesis of Diabetes mellitus, insulin resistants
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| EOI:
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| DOI:
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https://doi.org/10.31838/ijpr/2021.13.02.283
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| Download:
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