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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Assessment of Anti-inflammatory Activity of Bark of Prosopis cineraria (L.) Druce

Author: UPLOADED BY-ADMIN, ANIRUDH KHATRI, ANITA RATHORE, U.K. PATIL
Abstract: The purpose of the present study was to investigate the anti-inflammatory activity of the bark of Prosopis cineraria (L.) Druce. Petroleum ether, methanolic and aqueous extracts of bark of Prosopis cineraria at the doses of 25, 50 and 75 mg/kg were evaluated separately for anti-inflammatory activity in albino rats using carrageenan paw edema method. Methanolic extract of Prosopis cineraria was found to suppress carrageenan induced edema significantly (38.21%, 45.22% and 56.68% inhibition, P<0.01) at the doses of 25, 50&75 mg/kg, Whereas Indomethacin reduced it by 69.42%. It is presumed that the anti-inflammatory activity is due to the combined effect of various phytoconstituents reported for methanolic extract upon phytochemical investigation.
Keyword: Prosopis cineraria, Anti-inflammatory, Edema, Carrageenan
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