*Five Years Citation in Google scholar (2016 - 2020) is. 1451*   *    IJPR IS INDEXED IN ELSEVIER EMBASE & EBSCO *         Journal is Currently Not Indexed in Scopus as on february 2021 list Updated by scopus

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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Sensitivity Enhanced Study of Toluene and Acetonitrile Mixtures for Improved Pharmacovigilance Employing a Fiber Optic U-Shaped Glass Sensor

Author: , DR.S.VENKATESWARA RAO, S.SRINIVASULU
Abstract: Various kinds of designs have been proposed in the construction and development of fiber optic sensors for the measurement of numerous environmental parameters for the last few decades across the globe. A partially clad removed optical fiber was proved to sense various kinds of liquid parameters in which an uncladded sensing zone was immersed to a sufficient depth, offers a high degree of sensitivity and precision over wide dynamic ranges of parameters. The measurement of sensitivity of physical and chemical parameters plays a major role in the preparation, production, final testing of the products and hence to undertake pharmacovigilance in the pharmaceutical industry. In the present study the design, constitution, fabrication and characterization of a PCS optical fiber multi-parameter sensing device based on the principle of cladding mode spectral absorption dependent optical output power at room temperature (303.15K) and at operating wavelength of 660nm using a set of binary mixtures with a combination of Toluene and Acetonitrile is described. The sensor was implemented to measure refractive index, density, viscosity, ultrasonic velocity and their supplementary parameters at a high degree of accuracy and sensitivity and was found to be robust, reliable and versatile with all the advantages offered by optical fiber communication technology.
Keyword: Accuracy, Dynamic range, Multi-parameter, Output power, Pharmacovigilance, Sensing zone, Sensitivity.
DOI: https://doi.org/10.31838/ijpr/2021.13.02.430
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