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Assessment of Holothuria Atra Extracts Against Synthetic Textile Dyes Induced Endocrine Disorders, Biochemical and Genetic Alterations in Nile Tilapia (Oreochromis Niloticus)
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| Author:
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RAGAA F FATHY, ABDEL-RAHIM E A, SHALLAN M A, WAGDY K B KHALIL, SAMAH M BASSEM, FAGR KH ABDEL-GAWAD
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| Abstract:
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Textile dyes effluents, which are disregarded as a result of the textile industry's disposal into the water systems, have been noted to have a potential role of aquatic life pollution including aquatic organisms, through causing alterations in the function of pituitary cells. These textile dyes are affecting the synthesis of sex steroid
hormones which in return leads to endocrine disruption. The impact of some reactive textile dyes (RTDs) such as RY18 RB4 was investigated in this study against the health of Nile tilapia. Upon performing this study,
results revealed that the alterations in the mRNA expression of some HPG-axis genes were observed in Nile tilapia exposed to RTDs compared to negative control and treated animals with H. atra. Such results then suggested that using H. atra as dietary supplements could reduce the adverse impacts of FSHß, LHß and
CYP19A1 genes by RTDs, decreasing the incidence of endocrine disruptions in the Nile Tilapia.
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| Keyword:
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Holothuria atra, textile dyes, endocrine disorders, Nile tilapia.
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| EOI:
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| DOI:
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https://doi.org/10.31838/ijpr/2021.13.02.320
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| Download:
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