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An attempt in understanding the science of High dilution: Theory and Experiments.
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| Author:
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KANUPRIYA , ADITYA DILIPKUMAR PATIL
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| Abstract:
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Introduction: Many alternative treatment modalities have multi-target effects, strengthening host defences more than directly destroying infectious agents. Many herbs and homeopathic medicines act as stimulant, nontoxic agents that increase the body’s susceptibility to adapt stress or environmental change without relying on specific local treatments.As a result, a practical challenge with some traditional treatments has the poor assimilation to prevent clinical effects for treating an infectious process, which makes conventional pharmacological agent more potent but with more side effects. Homeopathy has historically raised doubts because of its methods of preparation by manner of dilutions and succession’s (vigorous shaking).The end product after dilution process is found to be crossing limit of the Avogadro’s number (6.024 x 10-23) which resembles 12 C (Centesimal scale) or 24 X (Decimal scale) of potency in homeopathic science.This makes researches a challenge to identify the pharmacokinetics and pharmacodynamics understanding of homeopathy .The aim of this review study is to enlighten the scope of homeopathic medicine ascertain embedded curative action previous proofed with various preclinical research, scientifically hypothesised with various models and providing the future perspective of research in this cutting age era.
Method and Material: The comprehensive search of literature was conducted from August 2019 followed by search databases from Google Scholar, Pub-med, web of science, conference proceeding. Search keywords like Homeopathy/Homoeopathy, Mechanism of action, Ultra high dilutionand Hypothetical models were used in various permutations and combination.
Results and Discussion: This review highlights the details of 22 research article published by various researchers across the globe. Information was categorized as Hypothesized and Hypothesized & Review on each research manuscript and had been documented. Research article highlighting correlation of Homoeopathic medicine through linear or non-linear pharmacological evidence with established theories are included in this review paper. It was unable to use any quality assessment checklist for research manuscript which had highlighted in this review article.
Conclusion: Homeopathic system of medicine over the decades have proven that its pharmacology and structural activity relationship in the domain of nanoparticles might be a new arena for research and might be novel drug delivery system for development. Researchers and fellow members need to decipher the further aspects of research in above mentioned domains.
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| Keyword:
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Homeopathy, Mechanism of action, Pharmacology, High dilution.
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| EOI:
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| DOI:
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https://doi.org/10.31838/ijpr/2021.13.02.467
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| Download:
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