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Study of Biochemical Parameters Among Patients of Polycystic Ovarian Syndrome in A Tertiary Care Hospital
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| Author:
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NISHTHA , DR PUSHPA DURGAWALE
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| Abstract:
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Background: PCOS is among the most common endocrinopathy in women of reproductive age group with
increasing prevalence worldwide either due to dietary or lifestyle changes or due to the involvement of genetic
background. It is diagnosed in a woman with 1. Oligomenorrhoea/amenorrhea 2. Clinical/Biomedical signs of
Hyperandrogenism, Hirsutism, Acne, Alopecia, elevated androgen levels (testosterone) 3. Presence of
polycystic ovaries on ultrasound scans. This study is planned to assess the biochemical parameters, fasting
glucose, fasting insulin, uric acid and lipid profile in women with PCOD. The parameters will be reported to
see the risk of development of CVDs.
Method: The study was conducted at Krishna hospital, Krishna Institute of Medical Sciences, Karad- a tertiary
care teaching institute. A total of 39 samples were studied of ultrasound diagnosed cases of PCOD and
analysed in biochemistry laboratory, Krishna hospital. The statistical software SPSS versions were used for the
analysis of collected data from PCOS patients and control group and Pearson correlation between the study
variable was performed to find out the relationships.
Result: The present study showed increased fasting blood glucose in 23% cases and hyperinsulinemia in 28%
cases suggestive of increased risk of developing diabetes in PCOS patients. A significant deviation of serum uric
acid towards the higher range of reference value and an increase in the Cholesterol, LDL, VLDL, TGL and a
slight deviation of HDL towards the lower range of the reference value indicate dyslipidemia. The above result
may predict CVD risk in PCOS patients.
Conclusion: The study revealed hyperinsulinemia and an increase in FBS along with dyslipidemia to be a risk
factor for developing CVD and diabetes among PCOS patients.
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| Keyword:
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PCOS, FBS, INSULIN, URIC ACID, LIPID PROFILE.
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| EOI:
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| DOI:
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https://doi.org/10.31838/ijpr/2021.13.03.013
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| Download:
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