*Five Years Citation in Google scholar (2016 - 2020) is. 1451*   *    IJPR IS INDEXED IN ELSEVIER EMBASE & EBSCO *       

logo

INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
ISSN
0975-2366
Current Issue
Article In Press
No Data found.
ADOBE READER

(Require Adobe Acrobat Reader to open, If you don't have Adobe Acrobat Reader)

Index Page 1
Click here to Download
IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

Click to download
 

Article Detail

Label
Label
A comprehensive review of floating microspheres

Author: ABDUL KAREEM S, AKILADEVI D, JEEVARAJ S
Abstract: Oral controlled release systems are designed to release drugs in a controlled manner in the body with precision to improve effectiveness, reduce side effects, and maximize medication bioavailability. The gastric contents are likely to keep floating drug delivery systems (FDDSs) buoyant for a long time. Hollow microspheres, granules, powders, salts, capsules, pills, and laminated films are among the various buoyant preparations. Along with their wide applicability in drug distribution to the stomach, floating microspheres are gaining prominence. Noneffervescent, gastro-retentive floating microspheres (Hollow Microspheres) In the strictest sense, hollow microspheres are spherical empty particles without a nucleus, free-flowing powders consisting of proteins or plastic polymers with a size spectrum of 1-1000 micrometres. Low-density structures with enough buoyancy to float over gastric contents and sit in the stomach for a prolonged period of time are known as gastro-retentive floating microspheres. Since the drug is released at a constant rate, it increases gastric stability and decreases variance in plasma drug concentration. Floating microspheres can increase the therapeutic efficacy of short halflife medications by lowering dosing frequency, which improves patient compliance. Enhanced absorption of drugs that only dissolve in the stomach, and increased gastric retention time due to buoyancy. Solvent diffusion and evaporation processes are used to build the hollow inner structure of floating microspheres.
Keyword: Floating drug delivery systems, Gastro-retentive floating microspheres, Ionotropic Gelation Method, Gastric retention, hollow microspheres
DOI: https://doi.org/10.31838/ijpr/2021.13.03.072
Download: Request For Article
 




ONLINE SUBMISSION
USER LOGIN


Username
Password
Login | Register
News & Events
SCImago Journal & Country Rank

Terms and Conditions
Disclaimer
Refund Policy
Instrucations for Subscribers
Privacy Policy

Copyrights Form

0.12
2018CiteScore
 
8th percentile
Powered by  Scopus
Google Scholar

hit counters free