*Five Years Citation in Google scholar (2016 - 2020) is. 1451*   *    IJPR IS INDEXED IN ELSEVIER EMBASE & EBSCO *       

logo

INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
ISSN
0975-2366
Current Issue
Article In Press
No Data found.
ADOBE READER

(Require Adobe Acrobat Reader to open, If you don't have Adobe Acrobat Reader)

Index Page 1
Click here to Download
IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

Click to download
 

Article Detail

Label
Label
Self-Emulsifying Drug Delivery Systems: A Review

Author: , M.SARITHA , D.REVATHI, P.V.KAMALA KUMARI, Y.SRINIVASA RAO
Abstract: Self emulsifying drug delivery systems (SMEDDS) are vital methods to increase bioavailability of poorly soluble drugs by increasing solubility. As oral route is most preferred route of administration due to its painless application and the major problem faced by this route includes decreased bioavailability which lead to importance of evaluation of Self emulsifying drug delivery systems. Self micro emulsifying drug delivery systems especially preferred primarily because these are physically stable , easy to manufacture, can be filled in soft gelatin capsules and then will generate a drug containing micro emulsion with a large surface area upon dispersion in the gastro intestinal tract. Various components like surfactants, lipids, co-surfactants used to formulate self micro emulsifying formulations (droplet size <100nm) which contribute to overall improvement in oral bioavailability via promoting the lymphatic transport, there by hepatic 1st pass metabolism suppressed. The present paper provides information on formulation, physiochemical & bio-pharmaceutical aspects of SMEDDS along with factors affecting & evaluation of SMEDDS.
Keyword: SMEDDS, Bioavailability, Surfactants, Co-Surfactant.
DOI: https://doi.org/10.31838/ijpr/2021.13.03.096
Download: Request For Article
 




ONLINE SUBMISSION
USER LOGIN


Username
Password
Login | Register
News & Events
SCImago Journal & Country Rank

Terms and Conditions
Disclaimer
Refund Policy
Instrucations for Subscribers
Privacy Policy

Copyrights Form

0.12
2018CiteScore
 
8th percentile
Powered by  Scopus
Google Scholar

hit counters free