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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Evaluation of antimicrobial activity and biofilm inhibition potential of Nelumbo nucifera Seed Extract Encapsulated Silver Nanoparticle

Author: SEEMAB SIDDIQUI, PANKAJ KUMAR RAI, RUCHI SINGH, DINESH KUMAR
Abstract: The present investigation is aimed to synthesized Nelumbo nucifera seed extract fabricated silver nanoparticles using the simple bio-reduction method. The synthesized nanoparticles showed the characteristic UV-vis absorption peak between 420- 435nm due to the plasmon resonance of nanoparticles. The FTIR analysis depicts the bonds, involved in stabilizing and encapsulating the nanoparticle. The diameter of the nanoparticles was found in the range between 10nm -30nm using Dynamic light scattering. Zeta potential was measured using a zeta nano sizer to determine the stability of the nanoparticle and it was found to be-30mV. Further, the structure of the nanoparticle was analyzed by TEM. The nanoparticles thus synthesized are screened for antimicrobial activity against bacterial pathogens using the well diffusion method. The nanoparticles were also evaluated for the efficacy of biofilm inhibition using biofilm inhibition assay.
Keyword: Nelumbo Nucifera, Silver Nanoparticle, Antimicrobial, Biofilm
DOI: https://doi.org/10.31838/ijpr/2021.13.02.494
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