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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Predicting Risk Stratification In Hypertrophic Cardiomyopathy With Fibrosis Burden And Scar Index Score With Cardiac Mri

Author: MARZIEH MOTEVALLI, SANAZ ASADIAN, ALI ALLAME, SHIMA BANITABA
Abstract: Hypertrophic cardiomyopathy (HCM) is thickening of cardiac muscles on the bases of different genetic mutations and underlying complex etiology that resulting in HCM and following severe complication like mid-ventricular obstruction, sudden cardiac death (SCD), heart failure and ventricular tachycardia. Considering such impermanence, procedures to predicting the disease behavior and complications are extremely imperative . Hence, we decided to study about role of late Gadolinium enhancement (LGE )in the prediction of severe complications in patients with hypertrophic cardiomyopathy. For this aim we enrolled 30 HCM patients with mean age of 38.50 ± 16.54 and following them during an average 17 months for related HCM complications Data have been shown that there was a relation between LGE score and incidence of cardiac events in patients who had LGE extent in their CMR imaging. Although the area under the curve of parameters represent the ability of LGE in prediction of cardiac complications. LGE on CMR can provide a useful way to determining and predicting HCM complications. Some of these complications are life-threatening and prediction of them could prevent catastrophic complications. Current study has shown the reliable role of LGE in prediction of such complications.
Keyword: hypertrophic cardiomyopathy (HCM), late Gadolinium enhancement (LGE), cardiac magnetic resonance imaging (CMR)
DOI: https://doi.org/10.31838/ijpr/2021.13.03.182
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