|
In-Vitro Anti-psoriatic activity of the Siddha herbal drug “Maha manjishtathi kashayam” using human keratinocyte HaCaT cell lines
|
|
| Author:
|
NANDHINI ,
|
| Abstract:
|
Psoriasis is an autoimmune skin disorder characterized by well defined slightly raised, dry erythematous maculae’s with silvery Scales, and typical extensor distribution. It affects approximately 2-3% of the population worldwide. 1, 50,000 -2, 60,000 new cases of psoriasis are diagnosed each year. About 400 people die from complications caused by psoriasis every year. About 11% patients have psoriatic arthritis. Although synthetic drugs exhibit quicker efficacy, there are at present, unsubstantiated opinion of higher incidents of adverse reactions following the use modern drugs when compared with herbal remedies. These remedies are in sync with nature, which is the biggest advantage. Maha manjisthathi kashayam (MMK), a effective Siddha herbal drug consist of ingredients such as thriphala, seendhil, maramanjal which has an good antioxidant and anti psoriatic properties. The main aim of the present investigation is to evaluate the anti-psoriatic potential of the formulation MMK using standard optimized HaCaT cell lines. The result obtained from the study reveals that the percentage of HaCaT cell viability decrease with increase in concentration of the siddha formulation MMK.
|
| Keyword:
|
Psoriasis, Siddha, MMK, HaCaT cell line, Ant psoriatic activity.
|
| EOI:
|
-
|
| DOI:
|
https://doi.org/10.31838/ijpr/2022.14.03.008
|
| Download:
|
Request For Article
|
|
|