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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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In Silico Studies of Some Derivatives of Aloe Vera

Author: M.ARUNA KUMARI, B.NAGARAJU, CH.KIRAN KUMAR, K.SHALINI, J.KRISHNA KISHORE
Abstract: Drug-likeness and pharmacokinetic properties of ten Aloe vera derivatives (1-10) was predicted using molinspiration software and swiss ADME online server. All these compounds were following Lipinski’s rule. Further these compounds were analysed for bioactivity score and pharmacokinetic properties. In these, compound 4 showed good bioactivity score and all the compounds (1-10) showed moderate pharmacokinetic properties.
Keyword: Aloe Vera, Anthraquinone, Drug-likeness, Bioactivity Score, ADME Prediction.
DOI: https://doi.org/10.31838/ijpr/2019.11.04.528
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