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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Novel Synthesis of Impurity A, B, and C of Antidepressant Drug Trazodone

Author: R.A.RANE , M.R.SURYAWANSHI, G.V.BABHULKAR, P.D.KHOBRAGADE, R.K.PATIL, R.D.MALE, S.A.CHINDHE, D.K.PAWAR
Abstract: Trazodone is a triazolopyridine analogue from the antidepressant class of serotonin receptor antagonists and reuptake inhibitors (SARIs). In the API and finished product of Trazodone impurity A, B and C are observed regularly. The present work discloses the first synthesis of these impurities with good to excellent yield and purity.
Keyword: Trazodone, Impurity, Synthesis
DOI: https://doi.org/10.31838/ijpr/2023.15.03.001
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