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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Concoction Of Herbal Extract and Application on Fabric To Develop Facemask A Potential Element Against Respiratory Infections

Author: KAVIYALAKSHMI MANIKANDAN, MEKALA MANI
Abstract: World has witnessed several pandemics and epidemics due to the existence of multiple airborne pathogens. The elevated air pollution results in spread of different types of air-borne infections such as COVID-19, Influenza, Chicken pox, Measles, Mumps etc., leads to respiratory ailments. World Health Organization (WHO) and Centres for Disease Control and Prevention (CDC) suggest wearing a facemask to prevent the ailments caused by the mutated strains and pathogens. Most commonly used facemask is Surgical facemask, made of plastic derivatives, polypropylene which leads to microplastic pollution. The environmental contamination can be reduced by proper use of fabric facemasks. The current study involves the development of fabric facemask incorporated with medicinal plant extract to prevent the serious air-borne complication and to avoid pollution. The herbal composite prepared from the methanolic extract of Glycyrrhiza glabra and Aloe vera shows minimum inhibition range from 3.1mg to 50mg against the microorganisms. The antioxidant and anti-inflammatory activity of the plant extract were analysed. The FT-IR spectrum of both extracts indicates a strong peak at 1018.41 cm-1 and 1026.13 cm-1confirms the presence of fluoro group. The GC-MS analysis of Glycyrrhiza glabra determines the presence of 13 antimicrobial compounds,4-O-Methylmannose (25.83%) abundant with retention time of 14.674. Whereas the chromatogram of Aloe vera confirms 17 antimicrobial compounds, in which 1,2,3-Benzenetriol (21.40%), n-Hexadecanoic acid (19.72%), and 9,12,15-Octadecatrienoic acid, (Z, Z, Z) (22.04%) were abundant with retention time 10.775, 16.463 and 17.863. The fabric incorporated with the selected plant composite ensures increased antimicrobial activity against the microorganisms.
Keyword: facemask, microplastic pollution, Glycyrrhiza glabra, Aloe vera, composite, FTIR, GCMS.
DOI: https://doi.org/10.31838/ijpr/2023.15.03.003
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