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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Simultaneous Estimation of Nebivolol Hydrochloride and Hydrochlorothiazide in Bulk and Tablet Dosage Form by QAnalysis Method.

Author: UPLOADED BY-ADMIN, K V SHAH, B L THUMBER, T R DESAI
Abstract: We have developed novel, simple, sensitive, rapid, accurate and economical spectrophotometric method for simultaneous estimation of Nebivolol Hydrochloride and Hydrochlorothiazide. In this method, absorbances are measured at two wavelengths, one being the isoabsorptive ? (?1) and the other being ?max of one of the sample components (?2). Both the drugs obey Beer’s law in the concentration ranges employed for this method. Result of the method was validated statistically as well as by recovery studies.
Keyword: Nebivolol Hydrochloride, Hydrochlorothiazide, Thiazide diuretics, antihypertensive,? – blockers, Spectrophotometric analysis, Q-Analysis method
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