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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Transmission Electron Microscopic studies on the effect of Acacia arabica against Cotylophoron cotylophorum

Author: ASHWINI RAMESH, DR.L.VEERAKUMARI, K.LALHMINGCHHUANMAWII
Abstract: Cotylophoron cotylophorum (Fischoeder, 1901) is a gastrointestinal parasite, primarily occurring in the rumen of livestock. Paramphistomosis, the disease caused by this digenetic trematode is responsible for considerable economic losses. The objective of this study is to investigate the effect of Acacia arabica on the internal architecture of Cotylophoron cotylophorum. A detailed study of the structural changes of AaEE-treated flukes has been carried out using transmission electron microscope. Prominent changes observed in the drug-treated flukes include necrosis in the parenchyma and ovaries. The nucleus and mitochondria were swollen and partly destroyed.
Keyword: Paramphistomosis, Cotylophoron cotylophorum, Acacia arabica
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